📘 قراءة كتاب Milk and blood levels of silicon and selenium status in bovine mastitis أونلاين
Milk and blood levels of silicon and selenium status in bovine mastitis من كتب طب بيطرى
467
Veterinary
Research
Communications,
11
(1987)
467-477
Gee
Abstracts
Ltd,
Norwich
-
printed
in
England
MILK
AND
ElLOOD
LEVELS
OF
SILICON
AND
!XLENIUM
STATUS
IN
6OVDE
MASTITIS
J.
PARANTAINENl,
E.
TENHUNEN2,
ATROSH+*
R.
KANGASNlEMI3,
S.
SANKAK14
iic
F.
1.
Research
laboratories,
Medica
Pharmaceutical
Co.
Ltd,
P.D.Box
325,
00101
Helsinki
10,
2.
Research
Center,
Neste
Oy,
06850
Kullo,
3.
Institute
of
Veterinary
Medicine,
University
of
Helsinki,
Helsinki
71,
4.
Department
of
Biochemistry,
College
of
Veterinary
Medicine,
Helsinki
55,
5.
Department
of
Pharmacology
and
Toxicology,
College
of
Veterinary
Medicine,
P.O.Box
6,
00551,
Helsinki,
Finland
*To
whom
all
correspondence
should
be
addressed.
(Accepted:
11
February
1987)
ABSTRACT
Parantainen
J.,
Tenhunen
E.,
Kangasniemi
R.,
Sankari
S.
&
Atroshi
F.
Milk
and
blood
levels
of
silicon
and
selenium
status
in
bovine
mastitis.
Veterinary
Research
Communications
11(5),
467-477
Milk
and
blood
levels
of
silicon,
selenium
and
the
selenoenzyme
glutathione
peroxidase
(GSH-Px)
were
measured
in
20
healthy
and
21
mastitic
cows.
In
milk
sarnples
from
healthy
quarters
the
mean
silicon
concentration
was
0.81
and
in
affected
ones
0.39
ppm.
In
serum
the
mean
silicon
values
were
1.63
and
1.02
ppm
respectively.
The
selenium
status
was
not
altered
but
the
level
of
erythrocyte
GSH-Px
was
lowered
in
mastitic
animals.
Silicon
is
known
to
have
marked
effects
on
free
radical
formation,
lipid
peroxidation
and
macrophage
activity.
Its
possible
role
in
infection
and
inflammation
is
evaluated.
Some
of
the
functions
of
silicon
may
resemble
those
of
selenium.
The
possibility
of
lowered
levels
of
silicon
and
of
the
selenoenzyme
in
mastitis
calls
for
experimentation
with
dietary
or
pharmaceutical
supplementation
of
these
trace
elements.
INTRODUCTION
Mastitis
is
the
most
economically
devastating
disease
of
dairy
cows,
causing
serious
problems
of
diagnosis
and
treatment.
Mastitis
has
been
defined
as
inflammation
of
the
mammary
gland
usually
resulting
from
infectious
processes
in
the
udder.
Milk
stagnating
in
a
blocked
duct
provides
an
ideal
medium
for
proliferation
of
bacteria.
However,
there
are
cases
of
mastitis
in
which
no
pathogens
are
found.
Pathogens
may
be
rnissed
in
routine
bacteriological
tests
(Schulze
et
al.,
1978)
but
there
is
also
the
possibility
that
the
disease
presents
itself
as
a
‘sterile
inflammation’
without
involvement
of
bacteria.
Gunther
(1965)
suggested
that
the
stagnated
milk
may
leak
into
the
surrounding
tissue,
provoking
inflammation
as
a
defence
reaction.
It
is
thus
obvious
that,
in
addition
to
pathogens,
other
factors
predisposing
the
udder
to
inflammation
are
important.
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